Synthesis and characterization of selected methyl 5-methoxy-2-methyl-1-benzofuran-3-carboxylate derivatives with potential antimicrobial activity.

نویسندگان

  • Mariola Krawiecka
  • Bozena Kuran
  • Jerzy Kossakowski
  • Irena Wolska
  • Marta Kierzkowska
  • Grazyna Młynarczyk
چکیده

Halogen and aminoalkyl derivatives of methyl 5-methoxy-2-methyl-1-benzofuran-3-carboxylate were prepared using 5-hydroxy-2-methyl-3-benzofuranocarboxylic acid as starting material. (1)H-NMR spectra were obtained for all of the synthesized structures, and for compounds 1 and 2 X-ray crystal structures were obtained too. All derivatives were tested for antimicrobial activity against a selection of Gram-positive cocci, Gram-negative rods and yeasts.

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عنوان ژورنال:
  • Acta poloniae pharmaceutica

دوره 69 6  شماره 

صفحات  -

تاریخ انتشار 2012